Objective
The aim of this study was to evaluate
the clinical applicability of the dental implant made of
nano-hydroxyapatite/polyamide-66（nHA/PA-66）composite according to the animal experiment.Methods 13 implants, which were made of nHA/PA-66
composite, were randomly implanted into the fresh tooth extraction wound in the
anterior teeth region of five adult mongrel dogs. The five dogs were sacrificed
singly at 4, 8, 12, 16 and 20 weeks postoperatively. Histological and
radiographical analyses were performed after the animals were sacrificed.Results In addition to one implant fallen off after 8
weeks, the rest of the 12 plants existed well. X ray examination, the gaps
between the implant and alveolar bone were no significant broadening or
narrowing. Hematoxylin-eosin staining histological examination, there were
connective tissues formed in the gaps. We also found that its quantity
gradually increased and its orientating changed over time.Conclusion The study
confirmed that the connective tissues formed in the gaps between the implant
and alveolar bone. We wonder that the connective tissues came from healthy
periodontium of alveolar fossa or fiber wrapping surrounding the implants. The
further study should be continued.
