Bone morphogenetic protein（BMP） is a kind of bioactive molecules with the ability to induce new bone formation, combined with a variety of biological materials to create various delivery systems for clinical bone repair. The establishment and application of the release system of BMP and collagen is the focus of current research, among which the binding mode of BMP and collagen is the most important. In this paper, the commonly used collagen materials of the release system of BMP and collagen as well as the binding mode of BMP and collagen are reviewed.
