Objective This study aims to analyze the clinical data of Uyghur cases of cleft lip and palate to provide more information on the prevention for this malformation. Methods Two hundred and twenty-five cases were collected from patients treated in the People’s Hospital of Xinjiang Uyghur Autonomous Region, from January 2009 to August 2012. A retrospective clinic study was carried out. Results The study included 18 cases of cleft lip, 115 cases of cleft lip with cleft palate, and 80 cases of cleft palate. The cases of unilateral cleft lip with or without palate cases were higher than the bilateral cases. In all cases, patients who were born in July to September were fewer than those born in other seasons. Most of the parents of the patients were from the countryside. Fifty-five cases had mothers underwent danger factor. Conclusion The ratio of cleft lip with cleft palate was higher than the other types in Uyghur patients. The cases of unilateral cleft lip with or without palate cases were more than the bilateral cases, and males were more than females. The cleft lip and/or palate formation may be related with multiple genes and environmental condition in the early stage of the embryo.
