In the development of stomatology, various dental restorative materials are applied in clinical treatments. Restorative materials with different interface structures and chemical properties affect bioadhesion and biofilm development. In a saliva environment, the intrinsic properties of these materials are deteriorated by the acquired pellicles to some extent; however, some of these properties can still occur through long-range force, thus affecting the development of biofilms. These materials can affect bioadhesion through different mechanical factors in the initial adhesion stage. Restorative materials can also release chemicals that affect the metabolism of biofilms. Composite resins, glass ionomer cements, ceramic materials, and metallic materials are common dental restorative materials. Investigation on the effect of these materials on biofilms can provide theoretical support for modification of dental materials.
