Vitamin D is a fat-soluble Vitamin that can be obtained from endogenous synthesis, dietary sources, and dietary supplements. Rickets and osteoporosis are well-known diseases associated with Vitamin D deficiency. Vitamin D deficiency is also associated with periodontitis. Vitamin D deficiency can increase the rate of periodontitis, severity of periodontitis, and rate of tooth loss. Individuals with adequate serum Vitamin D levels are more likely to maintain periodontal health. Appropriate serum Vitamin D levels can reduce the incidence of tooth loss and periodontitis, as well as promote wound healing. Vitamin D supplementation is important in maintaining periodontal health, especially for bleeding on probing, gingival index, and probing depth. Vitamin D can increase the alveolar bone density and inhibit alveolar bone loss. Vitamin D may be beneficial for oral health because of its direct effect on bone metabolism, and its ability to function as an anti-inflammatory agent and stimulate the production of anti-microbial peptides. This article reviews the research progress on Vitamin D, and the relationship between Vitamin D and periodontitis is analyzed.
