Calcium hydroxide(CH) is widely used as intracanal treatment during root canal therapy. However, calcium hydroxide remnants left in the root canal may influence the sealing ability of root canal filling, thereby compromising the quality of root canal therapy. This article compares the efficiency of eight different techniques of removing calcium hydroxide, including needle irrigation, passive ultrasonic irrigation, sonic irrigation, canalbrush, Endovac system, RinsEndo system, self-adjusting file system, and laser-activated irrigation, and provides information for clinical selection and application of these systems to remove CH medication from root canals.