Follicular helper T cell (Tfh) is a new subset CD4+T cells that is essential for maintaining the activity of germinal center and the balance of humoral immune. Recently, some studies have shown that Tfh played an important role in the immune microenvironment of T cell lymphomas, but there are fewer related studies in B cell lymphoma(BCL). This article reviews the role of Tfh in BCL through the classification and function of Tfh, the origin of BCL and it′s immune microenviroment, and the relationship between Tfh and immune microenviroment of BCL.
