Objective To determine the correlation between serum uric acid (SUA) and insulin secretion function in patients with pre-diabetes and type-2 diabetes mellitus (T2DM). Methods A total of 4 112 adult people participated in this study. They were divided into three groups according to the results of oral glucose tolerance test (OGTT): 493 with normal glucose regulation (NGR), 1 251 with impaired glucose regulation (IGR), and 2 368 with T2DM. Their levels of SUA, fasting insulin (FIns), 2 h post-meal insulin (2 h-Ins), and insulin resistance index (HOMA-IR) were determined. Correlations between SUA and insulin secretion and HOMA-IR were estimated. Results IGR patients had higher levels of SUA and 2 h-Ins compared with those with NGR and T2DM (PP
