Objective To investigate the expression of axis inhibition protein (AXIN) and metastasis-associated in colon cancer-1 (MACC1) in gastric carcinoma and their relationship to the clinicopathologic characteristics. Methods Expressions of AXIN and MACC1 proteins were examined by immunohistochemistry containing 100 specimens of gastric tissues (gastric carcinoma group) and 60 specimens of normal gastric mucosa tissues (control group, the nearby tissues of the excised specimen of gastric cancer patients, from the tumor of the gastric cancer >5.0 cm, and confirm that there were no cancer cells). Results The positive rates of AXIN and MACC1 proteins in gastric carcinoma and the control tissues were 37.0% vs. 83.3% and 58.0% vs. 6.7%, respectively. The difference were significant between the two groups (both PPr=-0.355, PP
