中文简化版孤独症谱系障碍量表-儿童版的信效度
Reliability and Validity of the Abridged Chinese Version of Autism Spectrum Quotient-Child form in China
作者：张漫雪, 杨平原, 胡霄, 郭奎芳, 司徒明镜, 黄颐
Author：ZHANG Man-xue, YANG Ping-yuan, HU Xiao, GUO Kui-fang, SITU Ming-jing, HUANG Yi
收稿日期：2018-01-06 年卷（期）页码：2018,49(4):599-603
期刊名称：四川大学学报（医学版）
Journal Name：JOURNAL OF SICHUAN UNIVERSITY （MEDICAL SCIENCE EDITION）
关键字：孤独症谱系障碍, 孤独症谱系障碍量表, 信度, 效度
Key words：Autism spectrum disorder, Autism-spectrum quotient, Reliability, Validity
基金项目：
中文摘要
目的 研究中文简化版孤独症谱系障碍量表-儿童版（autism-spectrum quotient，AQ）的信效度。 方法 方便取样抽取3所学校全部学生共6 896人（对照组），同时招募孤独症谱系障碍（autism spectrum disorder，ASD）患者86例作为病例组，所有被试均在专业人员指导下填写AQ量表；1个月后从对照组中随机抽取170人进行重测。计算AQ量表的信度和效度。 结果 入组时有效问卷为对照组6 472份，病例组86份，1月后对照组收集重测有效问卷159份。各分量表与总量表的相关性良好，为0.26~0.78，而各分量表之间相关性较小。对照组AQ总分在人群中呈连续性分布，类似于正态分布，偏斜度为-0.127，峰度为-0.124，说明AQ总分在人群中呈负偏态，稍平坦的分布。不同性别AQ得分有差异，男生组（42.09±9.92）高于女生组（40.07±9.94），且差异有统计学意义（Pr=0.06）。比较两组总量表和各分量表得分，发现病例组得分（54.49±14.16）高于对照组（41.12±9.98）（Pα系数为0.71，各分量表的系数为0.21~0.69；重测信度好，两次测量差异的平均值为0.09，且总量表和各个分量表两次测量差异均没有统计学意义（P>0.05）；全量表分受试者工作特征（ROC）曲线示曲线下面积（AUC）为0.78，最佳临床界值为48分，此时灵敏度为0.71，特异度为0.71。 结论 中文简化版AQ-儿童版具有良好的信效度，能适用于中国儿童，最佳临床界值为48分，在人群中呈连续性分布。
英文摘要
ObjectiveTo determine the reliability and validity of the abridged Chinese version of the autism spectrum quotient (AQ)-child form.MethodsA total of 86 children with autism spectrum disorder(ASD)were recruited from the West China Hospital from July 2014 to December 2016, along with 6 896 children recruited from three schools in Chengdu. The participants completed the AQ scale under instructions from a trained interviewer. Then 170 school children were selected and repeated the AQ scale within one month.ResultsAll subscale scores were correlated with the scale score, but with weak inter-subscale correlations. The total AQ score of the control group was continuously distributed in the population, which was similar to the normal distribution. The skewness was -0.127 and the kurtosis was -0.124, indicating that the total AQ score was negatively skewed and slightly flat in the population.There were differences in AQ scores between different genders in community children (Pr=0.06).The autistic children had a higher AQ score (54.49±14.16) than the school children (41.12±9.98)(Pαcoefficient of 0.71:ranging from 0.21 to 0.69 for the subscales. The test-retest reliability was good for the scale and the subscales (allP>0.05). The sensitivity and specificity of AQ for screening ASD was both 0. 71.ConclusionThe abridged Chinese version of the AQ-child scale has good psychometrics properties and may be a valid and reliable instrument for ASD screening with a cut-off score of 48.
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