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论文摘要

“益气活血”法治疗慢性阻塞性肺疾病稳定期(气虚血瘀证)的临床研究

Effects of “Reinforcing Qi and Activating Blood” on Stable Chronic Obstructive Pulmonary Disease (Qi Deficiency and Blood Stasis Syndrome)

作者:闵婕, 毛兵, 蒋红丽等

Author:MIN Jie, MAO Bing, JIANG Hong-li.et al

收稿日期:          年卷(期)页码:2014,45(4):601-605

期刊名称:四川大学学报(医学版)

Journal Name:JOURNAL OF SICHUAN UNIVERSITY (MEDICAL SCIENCE EDITION)

关键字:慢性阻塞性肺疾病 “益气活血”法 CD4 CD8 NO 内皮素

Key words:Chronic obstructive pulmonary disease “Reinforcing Qi and activating blood” therapy CD4 CD8 Nitrogen monoxidum Endothelin

基金项目:

中文摘要

目的 研究“益气活血”法治疗慢性阻塞性肺疾病(COPD)稳定期(气虚血瘀证)患者的临床疗效。 方法 选择COPD稳定期(气虚血瘀证)患者50例,随机分为对照组和治疗组。对照组给予基础干预,治疗组在基础干预的基础上加用玉屏风胶囊(2粒tid.)和复方丹参片(3片tid.)治疗,共治疗3月,观察12月。观察治疗前后的中医症状积分,评价中医证候疗效,观察细胞免疫指标及血流动力学指标的变化,同时对终点指标进行评价。结果 治疗组的总有效率在治疗3月和随访3月时明显优于对照组(PP+水平较疗前升高(P+水平降低(P+/CD8+比值升高(PPPPP

英文摘要

Objective To study the clinical effects of "Reinforcing Qi and Activating Blood" in the treatment of stable chronic obstructive pulmonary disease (Qi Deficiency and Blood Stasis Syndrome). Methods This study recruit 50 outpatients with stabe chronic obstructive pulmonary disease (Qi Deficiency and Blood Stasis Syndrome), who were randomly divided into 2 groups, control group and treatment of "Reinforcing Qi and Activating Blood" group. The patients in control group were given conventional treatment, while the patients in treatment group not only received conventional treatment but also the treatment of Yu-Ping-Feng capsules and Fu-Fang-Dan-Shen tablets for 3 months. The duration of follow up was 12 months, and chinese medicine (CM) symptoms, cellular immunity indexes and haemodynamics indexes were assessed every 3 months. Results The total effective rate in treatment group at 3 months treatment and 3 months follow-up were higher than that in control group(PPPPP>0.05), while the level of endothelin (ET) was significantly different (PP

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