Objective To investigate the prevalence and risk factors of hyperuricemia (HUA) in Tibetan monks of Sichuan province. Methods 755 adult Tibetan monks(more than 18 years old) in Ganzi Tibetan Autonomous Prefecture of Sichuan Province were included in this study for health examination. Residents of Kangding City who received health examination were selected as controls. We measured the height, body mass, waist circumference, hip circumference, blood pressure and detected liver and renal function, serum lipid and blood routine exam. Then HUA prevalence in different genders and ages, and risk factors of HUA were analyzed. Results The serum uric acid (SUA) level of Tibetan monks was (318.03±107.70) μmol/L with the total HUA prevalence of 21.46%. The prevalence of male was higher than that of female (25.44% vs. 19.02%,PPP