【Abstract】 Objective To study the expression of Bcl-2 and PD-L1 in colon cancer and its relationship with metastasis. Methods Tumor samples were collected from 57 cases of colon cancer, and tumor adjacent normal mucous tissue were obtained as normal control. The expressions of Bcl-2 and PD-L1 were assayed by immunohistochemical staining, and its correlations with patients’ clinical pathological indexes were analyzed. Results The positive rate of Bcl-2 protein was 75.43% and 52.63% in colon cancer tissues and tumor adjacent colon mucous tissue respectively, with statistically significant difference (P
