This study aimed to study the mechanism of the effect of Salvia miltiorrhizae-Angelica. The active ingredients of Salvia and Angelica and potential targets of candidate compounds were screened in TCMSP. And artificially retrieval of potential targets of candidate compounds through prediction platforms related to Alzheimer's disease. Target information was imported into the DAVID database and KEGG database for target and pathway analysis to construct the compound-target action network, target-pathway network graph, and compound-target-pathway graph. The results indicate that the active ingredients for Alzheimer's disease in Salvia and Angelica were β-sitosterol, stigmasterol, tanshinone Ⅱ, tanshinone, cryptotanshinone and dihydrotanshinone, which may play a role in Alzheimer's disease through mechanisms such as anti-inflammatory, anti-oxidant, immune system, cell cycle, calcium signaling pathway and neural receptor-ligand interaction.
