We used nuclear binding energy analytical formulas based on two nuclear structure models respectively (liquid drop model and nuclear sphere packing model), and selected 90 nuclides on the β-stability line and 152 nuclides which have α-decay capability for model analysis. The results show that: For β-stability line analysis, nuclear sphere packing model can better explain the relationship between proton number Z and atomic mass A than liquid drop model, while liquid drop model works better on α decay energy analysis.