Periodontal ligament contain multipotent stem cells which can differentiate into osteoblasts/cementoblasts, and responsible for remoldeling, trauma repair and regeneration of periodontal tissue. In the mean time, periodontal ligament have a capacity to inhibit mineralization, maintain structure and functional homeostasis. We summarized the differentiation capability of periodontal ligament cells and molecular biology basis of maintaining periodontal ligament structure and functional homeostasis.
