The enamel surface dissolution(demineralization) and reconstruction(remineralization) is a continuous process. Remineralization treatment of early caries has become an important research trend. Adding the different components, the morphology and properties of hydroxyapatite crystal are different. Good growth of minerals for clinical prevention and treatment of early enamel demineralization provide powerful experimental basis. This paper was reviewed the research of the effects of adding composition on enamel remineralization in vitro.