ObjectiveTo evaluate the effect of acellular dermal matrix(ADM) on guided bone regeneration(GBR) of the defects of jaw bone.MethodsWe collected 42 patients with bone defect of the recipient site before implantation visiting the department of stomatology of Chengdu Military Region Hospital of The People’s Liberation Army, and then used domestic ADM GBR to repair jaw bone defect. Examed with X-ray six months postoperatively, and compared the results with that of the GBR preoperatively. Then we implanted in the osteogenesis area, observated the bone formation conditions, made histopathologic study for new bone from implanting.Results42 patients after review of nonsignificant do not have between -group rejection. Phase of 40 patients underwent surgical process observation osteogenesis result is satisfactory, and planting primary stability is better without residual film. Histology observations show that there are obvious slice of bone formation, because of wound infection. One late osteoblast effect is satisfactory after repeated washing area with antibiotics. The other is failure.ConclusionThe effect of GBR with ADM for repairing oral maxillofacial bone defect is definite.