期刊导航

论文摘要

国产异种脱细胞真皮基质在引导骨再生术治疗种植义齿受植区骨缺损中的成骨效果评价

Domestic acellular dermal matrix in the treatment of guide bone regeneration the maxillofacial bone defect in planting area of oral performance evaluation

作者:陈红亮 赵承初 赵峰 钟科 孙勇

Author:Chen Hongliang, Zhao Chengchu, Zhao Feng, Zhong Ke, Sun Yong.

收稿日期:2012-08-12          年卷(期)页码:2013,40(1):33-36

期刊名称:国际口腔医学杂志

Journal Name:International Journal of Stomatology

关键字:颌骨骨缺损,异种脱细胞基质,引导骨再生,成骨效果,

Key words:mandibular bone defect,acellular matrix,guided bone regeneration,osteogenic effect,

基金项目:

成都军区“十一五”科研基金资助项目(MA07015)

中文摘要

目的 对异种脱细胞真皮基质(ADM)在应用引导骨再生(GBR)治疗种植义齿受植区骨缺损中成骨的效果进行评价,以确定ADM是否能够在GBR 术中有成骨作用。方法 收集中国人民解放军成都军区机关医院口腔科就诊的种植前受植区颌骨骨缺损的患者42 例为研究对象,采用国产异种ADM进行GBR术修复颌骨骨缺损,6 个后行X线检查,并与GBR术前进行比较,成骨区行种植术,观察术中骨生成的情况,将种植过程中取出的新生骨进行组织学观察。结果 42例患者在术后复查中未见明显排异反应。其中,40例患者行二期手术过程中观察成骨效果满意,种植体初期稳定性较好,未见残留膜。切片组织学观察可见明显板层骨形成。2例患者因为创口感染,经过术区抗生素反复冲洗, 控制感染后,1例后期成骨效果较满意,1例失败。结论 异种ADM应用于GBR修复种植义齿受植区骨缺损,成骨效果肯定。

英文摘要

ObjectiveTo evaluate the effect of acellular dermal matrix(ADM) on guided bone regeneration(GBR) of the defects of jaw bone.MethodsWe collected 42 patients with bone defect of the recipient site before implantation visiting the department of stomatology of Chengdu Military Region Hospital of The People’s Liberation Army, and then used domestic ADM GBR to repair jaw bone defect. Examed with X-ray six months postoperatively, and compared the results with that of the GBR preoperatively. Then we implanted in the osteogenesis area, observated the bone formation conditions, made histopathologic study for new bone from implanting.Results42 patients after review of nonsignificant do not have between -group rejection. Phase of 40 patients underwent surgical process observation osteogenesis result is satisfactory, and planting primary stability is better without residual film. Histology observations show that there are obvious slice of bone formation, because of wound infection. One late osteoblast effect is satisfactory after repeated washing area with antibiotics. The other is failure.ConclusionThe effect of GBR with ADM for repairing oral maxillofacial bone defect is definite.

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