口腔颌面部溶骨症

Gorham-Stout syndrome, which is also called massive osteolysis, vanishing bone disease, phantom bone disease, is characterized by spontaneous progressie bone resorption, and is a rare disorder in the clinical, whereas the etiology is unknown. Gorham-Stout syndrome is characterized histologically by the proliferation of endothelial-lined vessels in bone and by the replacement of bone with fibrous tissue. Clinical manifestations are diverse. In most cases, only a single bone or several bones are affected. Associated infiltrative soft tissue abnormality is often found. Reports of maxillofacial bone resorption are few. According to the literature of domestic and overseas, the aim of this paper is to make a brief review about the etiology, clinical manifestations, diagnosis and differential diagnosis and therapy of Gorham-Stout syndrome.