慢性牙周炎患者种植修复后种植体牙周指数及龈沟液炎性因子水平的变化研究

ObjectiveThis work aims to determine the changes in periodontal index and inflammatory factor levels in gingival crevicular fluid after implant restoration in patients with chronic periodontitis.MethodsA total of 40 patients with tooth-loss in chronic periodontitis and healthy periodontium were selected as the research and control groups, respectively, and were treated with implant restoration from June 2015 to June 2017. Probing depth (PD), modification plaque index (mPLI), papilla index score (PIS), modification sulcus bleeding index (mSBI) and marginal bone loss volume were detected and compared at 1, 3, and 6 months after implant restoration between the two groups. The interleukin (IL)-1β, IL-6, and IL-8 levels in gingival crevicular fluid of two groups were detected and compared.ResultsThe implant survival rate after implant restoration for the two groups were both 100%. Three months after implant restoration, IL-1β, IL-6, and IL-8 levels in the research group were significantly increased as opposed to the levels 1 month after implant restoration; and the mentioned levels in the research group are also higher than that of 3 months after implant restoration in control group (P<0 .05,P<0 .01). six months after implant restoration, the pd, mpli, msbi and marginal bone loss volume for the research group increased compared with that at 1 month after implant restoration; the mentioned results in the research group are significantly higher than that of 6 months after implant restoration in control group (P<0 .05,P<0 .01). the pis of the two groups showed no statistically significance (P>0.05).ConclusionThe short-term effect of implant restoration in chronic periodontitis patients is ideal, but the risk of peri-implantitis is higher on patients with healthy periodontium compared with the other group.