拟盘多毛孢属活性次级代谢产物的研究进展
Research progress on the active metabolites from the fungus Pestalotiopsis
作者：陈霈雯;彭家茵;陈茵宜;陶移文;
Author：
收稿日期： 年卷（期）页码：2019,34(05):-519-525
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：拟盘多毛孢属;活性代谢产物;内生真菌;抗肿瘤活性;抗细菌活性;抗真菌活性;抗病毒活性;抗寄生虫活性
Key words：
基金项目：广东省自然科学基金(2018A0303130201; 2016A030313588);;
广州市教育局项目(1201610155);;
广东省海洋与渔业厅专项资金(A201701607);;
广州医科大学大学生实验室开放项目(广医大发[2018]27号No.14),广州医科大学大学生创新项目立项(2017A083);;
广东省大学生创新训练项目立项(201810570081)
中文摘要
拟盘多毛孢属作为一种拥有丰富产物的内生真菌,已成为很多活性代谢产物的主要来源。本文整理总结了近年从拟盘多毛孢属中发现的活性代谢产物,以不同活性特点来分类,主要包括抗肿瘤、抗细菌、抗真菌、抗病毒和抗寄生虫活性等。
参考文献
[1] Wen C,Wu Y,Tian X. Recent advances and issues on the endophyte[J]. Chin J Ecology,2004,49(2):86-91.
[2] Ding G,Liu S,Guo L. Antifungal metabolites from the plant endophytic fungus Pestalotiopsis foedan[J]. J Nat Prod,2008,71(4):615.
[3]张军，罗都强．细丽拟盘多毛孢次级代谢产物研究[J]．亚太传统医药，2013,9(2):51-52.
[4] Bai ZQ,Lin XP,Liu YH. Research progress on the chemical constituents from the endophytic fungus Pestalotiopsis spp.[J]. Nat Prod Res,2013,25:706-715.
[5] Xing JG,Deng HY,Luo DQ. Two new compounds from an endophytic fungus Pestalotiopsis Heterocornis[J]. J Asian Nat Prod Res,2011,13(12):1069-1073.
[6]胡淑媛，罗都强，陈川．一种来源于植物内生真菌次级代谢产物的抗肿瘤活性研究[J]．中国卫生产业，2013,11(7):15-17.
[7] Guan YQ,Cao MM,Liu T,et al. Effect of secondary metabolites of endophytic fungus Pestalotiopsis adusta on He La cells[J]. Chin Trad Patt Med,2014,36(2):325-329.
[8] Li ZZ,Yang XL. A New Biphenyl from the fermentation broth of plant endophytic fungus Pestalotiopsis zonata isolated from Cyrtotachys lakka[J]. Mycosystema,2014,22(1):97-102.
[9] Xiao J,Hu JY,Sun HD,et al. Sinopestalotiollides A-D,cytotoxic diphenyl ether derivatives from plant endophytic fungus Pestalotiopsis palmarum[J]. Bioorg Med Chem Lett,2018,28:515-518.
[10] Jing Z,Gang L,Qin D,et al. Cytotoxic constituents from the mangrove endophytic Pestalotiopsis sp. induce G0/G1 cell cycle arrest and apoptosis in human cancer cells[J]. Nat Prod Res,2017,1(1478-6427).
[11] Lei H,Lin XP,Han Li,et al. Polyketide derivatives from a marine-sponge-associated fungus Pestalotiopsis heterocornis[J]. Phytochemistry,2017,142:51-59.
[12] Li CS,Yang BJ,James Turkson,et al. Anti-proliferative ambuic acid derivatives from Hawaiian endophytic fungus Pestalotiopsis sp. FT172[J]. Phytochemistry,2017,140:77-82.
[13] Lei H,Lin XP,Han L,et al. New metabolites and bioactive chlorinated benzophenone derivatives produced by a marinederived fungus Pestalotiopsis heterocornis[J]. Mar Drugs,2017,15(3):69-78.
[14] Liu L,Han Y,Xiao JH,et al. Chlorotheolides A and B,spiroketals generated via Diels? Alder reactions in the endophytic fungus Pestalotiopsis theae[J]. Nat Prod,2016,79(10):2616-2623.
[15] Liu S,Dai HF,Gamall Makhloufi,et al. Cytotoxic 14-membered macrolides from a mangrove-derived endophytic fungus,Pestalotiopsis microspora[J]. Nat Prod,2016,79(9):2332-2340.
[16] Xu MF,Jia OY,Wang SJ,et al. A new bioactive diterpenoid from Pestalotiopsis adusta,an endophytic fungus from clerodendrum canescens[J]. Nat Prod Res,2016,30(23):2642-2647.
[17] Liu Y,Yang MH,Wang XB,et al. Caryophyllene sesquiterpenoids from the endophytic fungus,Pestalotiopsis sp.[J]. Fitoterapia,2016,109:119-124.
[18] Xie J,Li J,Yang YH,et al. Four pestalpolyols from a mycoparasite Pestalotipsis sp. PG52[J]. Arch Pharm Res,2015:1-6.
[19] Li J,Xie J,Yang YH,et al. Pestalpolyols A-D,cytotoxic polyketides from Pestalotiopsis sp. cr013[J]. Planta Med,2015,81(14):1285-1289.
[20] Qi QY,Li EW,Han JJ,et al. New ambuic acid derivatives from the solid culture of Pestalotiopsis neglecta and their nitric oxide inhibitory activity[J]. Scienti Rep,2015,5:9958.
[21] Yuan C,Li G,Wang HY,et al. The metabolites of endolichenic fungus Pestalotiopsis sp.[J]. Mycosystema,2018,37(2):237-245.
[22] Hang XL,Xing Q,Ma J,et al. Research on chemistry and biological activities of a new natural product pestalactone from a soft coral-derived fungus collected from Xisha Island[J].Chin J Marine Drugs,2016,35(4):1-5.
[23] Yang XL,Zhang S,Song SJ,et al. A new biphenyl from the fermentation broth of plant Endophytic Fungus Pestalotiopsis zonata isolated from cyrtotachys lakka[J]. Chin J Nat Med,2011,9(2):101-104.
[24] Zhang L,Jia YL,Fang YW,et al. The chemical structures and bioactivities of cerebrosides isolated from the marine-derived fungus Pestalotiopsis sp. collected from Xisha Island[J]. Chin J Nat Med,2017,36(2):35-39.
[25] Kuang C,Jin SX,Liu Y,et al. Drimane sesquiterpenoids and isochromone derivative from the endophytic fungus Pestalotiopsis sp. M-23[J]. Nat Prod Bioprospect,2016,6(3):155-160.
[26] Yuan C,Ding G,Wang HY. Polyketide-terpene hybrid metabolites from an endolichenic fungus Pestalotiopsis sp.[J].Bio Med Res Inter,2017,2:6961928-6961937.
[27] Xu D,Zhang BY,Yang XL. Antifungal monoterpene derivatives from the plant endophytic fungus Pestalotiopsis foedan[J]. Chem Biodivers,2016,13(10):1422-1425.
[28] Song RY,Wang XB,Yin GP,et al. Isocoumarin derivatives from the endophytic fungus,Pestalotiopsis sp[J]. Fitoterapia,2017,122:115-118.
[29] Katsuyuki Sakai,Tomoyasu Hirose,Masato Iwatsuki,et al.Pestynol,an antifungal compound discovered using a saccharomyces cerevisiae 12geneΔ0HSR-i ERG6-based assay[J]. Nat Prod,2018,81(7):1604-1609.
[30] Wang JF,Liang R,Liao SR,et al. Vaccinols J-S,ten new salicyloid derivatives from the marine mangrove-derived endophytic fungus Pestalotiopsis vaccinii[J]. Fitoterapia,2017,120:164-170.
[31] PF Uzor,DC Odimegwu,W Ebrahim,et al. Anti-respiratory syncytial virus compounds from two endophytic fungi isolated from Nigerian medicinal plants[J]. Drug Res,2016,66(10):527-531.
[32] Li J,Xie J,Yu FX,et al. Pestalotic acids A-I,antibacterial ambuic acid analogues,from a mycoparasite(Pestalotipsis sp.cr014)of Cronartium ribicola[J]. Arch Pharm Res,2016:1-9.
[33] Jia YL,Wei MY,Chen HY,et al.(+)-and(-)-Pestaloxazine A,a pair of antiviral enantiomeric alkaloid dimers with a symmetric spiro[oxazinane-piperazinedione] skeleton from Pestalotiopsis sp.[J]. Org Lett,2015,17(17):4216-4219.
[34] Jia YL,Guan FF,Ma J,et al. Pestalotiolide A,a new antiviral phthalide derivative from a soft coral-derived fungus Pestalotiopsis sp.[J]. Nat Prod Sci,2015,21(4):227-230.
[35] Qian YX,Kang JC,He J,et al. Isolation and identification of secondary metabolites from the solid culture of endophytic fungal strain Pestalotiopsis uvicola GMH31 from Artemisia japonica[J]. Nat Prod Res Develop,2016,28:1732-1735,1757.
[36] Xia XK,Soonok K,Liu CH,et al. Secondary metabolites produced by an endophytic fungus Pestalotiopsis sydowiana and their 20S proteasome inhibitory activities[J]. Molecules,2016,21(7):E944.
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