藤黄酸抗肿瘤作用机制及其纳米制剂的研究进展
作者：白皎皎;陈新棉;曾代文;汤明海;童荣生;蔡璐璐;
Author：
收稿日期： 年卷（期）页码：2018,33(06):-546-549
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：藤黄酸;抗肿瘤;作用机制;纳米制剂;作用靶点;临床缺陷;靶向性;新方向;研究进展
Key words：
基金项目：四川省卫生和计划生育委员会科研课题普及应用项目(No.17PJ554);;
四川省人民医院临床研究及转化基金(No.2017LY08)
中文摘要
藤黄酸是从植物藤黄中提取的主要有效活性成分,近年来发现藤黄酸对多种肿瘤有明显疗效,其作用机制较多,作用靶点广泛。但藤黄酸自身仍具有一些缺点,限制了其在临床上的应用。新型纳米技术能够克服藤黄酸的这些缺点,为藤黄酸新制剂的研究与开发提供了一种新方向。文中综述了近5年来国内外有关藤黄酸抗肿瘤机制以及其纳米制剂方面的进展,可为藤黄酸的进一步深入研究提供参考。
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