甲磺酸多拉司琼与盐酸格拉司琼预防化疗致恶心呕吐的临床对照研究
作者：赵娅琴;王瑾;刘端祺;刘敏;陈宏;王辛;李志平;侯梅;
Author：
收稿日期： 年卷（期）页码：2015,30(01):-128-130
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：甲磺酸多拉司琼;盐酸格拉司琼;化疗;恶心;呕吐
Key words：
基金项目：
中文摘要
69例患者采用随机、双盲双模拟、自身交叉对照的临床研究方法,分别给予甲磺酸多拉司琼与盐酸格拉司琼,观察和比较患者化疗后急性呕吐、延迟性呕吐、恶心的发生及其安全性。对化疗后24 h内急性呕吐控制率、延迟性呕吐控制率、0~7 d恶心控制率、食欲改善有效率、24 h内平均解救人数发生率两组差异均无统计学意义,安全性评价的差异无统计学意义。甲磺酸多拉司琼与盐酸格拉司琼用于预防化疗所致的恶心呕吐,其有效性和安全性相似。
参考文献
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