手性螺环膦配体催化的不对称氢化反应在天然产物及药物合成中的应用
作者:李卫华;郑玉芹;张荣华;
Author:
收稿日期: 年卷(期)页码:2015,30(02):-259-262
期刊名称:华西药学杂志
Journal Name:WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字:手性膦配体;不对称氢化;天然产物;药物分子;对映选择性;过渡金属;络合物;催化
Key words:
基金项目:
中文摘要
手性螺环膦配体具有合成方便、结构多样等特点。这类配体与过渡金属形成的络合物能够催化多种不同底物的不对称氢化反应,表现了优异的对映选择性。同时,这些反应也被应用于天然产物和药物分子的合成中。
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