固体脂质纳米粒的研究进展
Research and development of solid lipid nanoparticles
作者：聂庆,孙晓宇,汪世龙,李文哲,姚思德
Author：
收稿日期： 年卷（期）页码：2005,(04):-328-331
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：固体脂质纳米粒;药物载体;制备方法;药物包封;药物释放
Key words：
基金项目：上海市科技攻关项目(03DZ19223)
中文摘要
目的综述固体脂质纳米粒的最新研究进展。方法以国内外大量有代表性的论文为依据,将固体脂质纳米粒的制备方法、特性分析、药物载入、药物释放及应用情况进行了概括,指出了发展前景和尚待解决的问题。结果固体脂质纳米粒的多种制备方法各有优、缺点,调整制备参数可调整药物的包封率和释药曲线。结论固体脂质纳米粒可供多途径给药,是极有发展前景的新型给药系统。
参考文献
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