增加吸入粉雾剂肺部沉积率的方法研究进展
作者:贺建东;付廷明;郭立玮;
Author:
收稿日期: 年卷(期)页码:2008,(05):-585-587
期刊名称:华西药学杂志
Journal Name:WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字:肺部给药;空气动力学粒径;表面性质;载体;细粉分布比例
Key words:
基金项目:教育部博士点基金(批准号:2006315007);;
江苏省教育厅自然科学基金(05KJD360155)
中文摘要
肺部给药具有很多传统给药方式所无法比拟的优点,近年来发展非常迅速,但同时生物利用度低也成为限制其发展的主要因素。特综述空气动力学粒径、表面性质、载体等影响生物利用度的因素对肺部给药积率的影响。
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