脂质体对水溶性药物包封方法的研究进展
作者：程晓丹;李学明;顾立;
Author：
收稿日期： 年卷（期）页码：2009,24(02):-194-197
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：脂质体;包封率;水溶性药物
Key words：
基金项目：
中文摘要
分析并归纳了对国内外提高水溶性药物脂质体包封率的最新方法和技术,为水溶性药物脂质体的研发和应用提供参考。
参考文献
[1]Igor V Z,Norbert M.Liposome-encapsulated vincristine,vin-blastine and vinorelbine:Acomparative study of drug loading andretention[J].J Contr Rele,2005,104:103?111.
[2]高晓黎,王梅.四种前体脂质体制剂的包封率比较及小肠吸收研究[J].新疆医科大学学报,2007,30(8):787-790.
[3]Maria L I,Paola B.Preparation,characterization,cytotoxicityand pharmacokinetics of liposomes containing lipophilic gemcit-abine prodrugs[J].J Contr Rel,2004,100:331?346.
[4]Lalanne M,Andrieux K.Liposomal formulation of a glycerolipid-ic prodrug for lymphatic delivery of didanosine via oral route[J].Inte J Pharmac,2007,344:62?70.
[5]李唐棣,梅兴国.重组人生长激素脂质体的制备及载药研究[J].中国生化药物杂志,2006,27(3):133-136.
[6]Maurizio R,Stefano G.Development of liposomal capreomycinsulfate formulations:Effects of formulation variables on peptideencapsulation[J].Inter J Pharmac,2006,311:172?181.
[7]Martin B,Markus D.Preparation and characterization of semi-solid phospholipid dispersions and dilutions thereof[J].Inter JPharmac,1998,170:187?199.
[8]Kaiser N,Kimpfler A.5-Fluorouracil in vesicular phospholipidgels for anticancer treatment:entrapment and release properties[J].Inter J Pharmac,2003,256:123?131.
[9]Ulrich M,Sanja C.Dual asymmetric centrifugation(DAC)—Anewtechnique for liposome preparation[J].J Contro Rel,2008,125:16?24.
[10]Jaroslav Tura′nek,Andrea Kasˇna.Preparation of Sterile Lipo-somes by Proliposome?Liposome Method[J].Methods in en-zymology,2003,367:111-125.
[11]Ruzˇica Galovic′Rengel,Karmela Barisˇic′.High efficiency en-trapment of superoxide dismutase into mucoadhesive chitosan-coated liposomes[J].Euro J Pharmac Sci,2002,15:441?448.
[12]Abdelbary MAE,Kiran KK.Formulations generated from ethanol-based proliposomes for delivery via medical nebulizers[J].JPharma Pharmaco,2006,58:887?894.
[13]蒋国强,朱德权.一种对水溶性药物有较高包封率的脂质体的制备方法[P].中国专利:200410096075.0,2005-07-06.
[14]Tomohiro I,Toshihiro G.Control of physicochemical properties ofliposomes using a supercritical reverse phase evaporation method[J].Langmuir,2003,19:2021-2025.
[15]Katsuto O,Takeshi S.Preparation of liposomes using an im-proved supercritical reverse phase evaporation Method[J].Langmuir,2006,22:2543-2550.
[16]Aristarchos P,Sophia H.A liposomal formulation of doxorubi-cin,composed of hexadecylphosphocholine(HePC):physico-chemical characterization and cytotoxic activity against humancancer cell lines[J].Biomedi Pharmacothe,2005,60:36?42.
[17]Nancy DS,Kelly AC.pHgradient loading of anthracyclines intocholesterol-free liposomes enhancing drug loading rates throughuse of ethanol[J].Biochimica et Biophysica Acta,2004,1661:47?60.
[18]Sheela AA,Katarina E.An evaluation of transmembrane ion gra-dient-mediated encapsulation of topotecan within liposomes[J].J Contro Rel,2004,96:449?461.
[19]王玮,周建平.主动载药法制备双氯芬酸钠脂质体及其体外释放[J].中国药科大学学报,2007,38(4):323?326.
[20]Chuanyun D,Bochu W.Preparation and characterization of lipo-somes-in-alginate(LIA)for protein delivery system[J].Colloids and Surfaces B:Biointerfaces,2006,47:205?210.
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