The growth and development of craniofacial pattern are related to the occurrence and development of malocclusion. Understanding the physiological mechanism of the growth and development of craniofacial structures are important for the improvement of early growth. In the process of orthodontic treatment, adequate attentions should be paid to the bones, teeth, muscles and other aspects, which are the basic elements that orthodontists must pay attention to the process of diagnosis and treatment. This paper is written based on the growth and development characteristics of cranial and facial structures and combined with the characteristics of growth improvement, the related knowledge of early orthodontic treatment was expounded in order to provide reference for orthodontists.