Prestressed steel reinforced concrete structure(PSRC) is composite structure, which has advantage of both prestressed reinforced concrete structure and reinforced concrete structure. In order to investigate the mechanical behavior and the law of moment redistribution, two large scale prestressed steel reinforced concrete frame were tested and their performance such as failure pattern, crack development, rigidity change were studied. The results show that PSRC is ductile failure and basically meets the plane section assumption. Based on experiments, the bearing capacity formulas considered secondary axial force were put forward. Test moment modulation is 30%,which is higher compared with prestressed reinforced concrete frame.