Objective To investigate the effects of Sol-Gel coating on the corrosion resistance of nickel-chronium alloys in vitro. Methods The bond strength of coating-substrate interface sintered at different temperatures（300, 400, 500, 600 ℃） was tested by scratching method. The Sol-Gel coating was analyzed by scanning electron microscope （SEM）, and its corrosion resistance was assessed by a static immersion method. Results The bond strength of coating- substrate interface reaches the peak at 400 ℃. The Sol-Gel coating can apparently inhibit the release of metal ions and improve the corrosion resistance of nickel-chromium alloy. Conclusion Sol-Gel coating can evidently improve corrosion resistance of the nickel-chromium alloy, which has great potential in prospective clinical practice．
