Objective To investigate the relationship between wedge - shaped defects and occlusal interference. Methods Following examination from 46 patients, a total of 157 teeth were identified to have the criteria set for wedge- shaped defects and regarded as the experiment group. Also, 157 adjacent teeth exhibiting no such noncarious cervical lesions were randomly selected from the same group of patients and regarded as the control group. The distribution of occlusal force and time were examined with T- ScanⅡ system in 46 patients with wedge- shaped defects in intercuspal occlusion position, protrusive movement and lateral movement. Occlusal interference and premature contact were evaluated and compared between the two groups. Results The proportion of the teeth with premature contact in experiment group was 6.37%, while the control group was 2.55%, there was no significant difference between the two groups(P>0.05). The total proportion with occlusal interferences in experiment group was 23.57%, which was significantly higher than that of the control group(10.19%, P