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论文摘要

口腔扁平苔藓患者白色念珠菌分离株的颊细胞粘附力研究

Adhesion to Buccal Epithelial Cells ofCandida albicansIsolates from Oral Lichen Planus

作者:曾昕;陈谦明;聂敏海;李秉琦

Author:ZENG Xin1,CHEN Qian-ming1,NIEMin-hai2,LIBing-qi1

收稿日期:2005-12-25          年卷(期)页码:2005,23(06):537-

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:白色念珠菌,粘附力,口腔扁平苔藓,

Key words:Candida albicans,adhesion to buccal epithelial cells,oral lichen planus,

基金项目:国家自然科学基金资助项目(30300387);“十五”国家科技攻关计划资助项目(2004BA720A28)

中文摘要

的 研究健康人和口腔扁平苔藓患者口腔白色念珠菌分离株的颊细胞粘附力。方法 应用颊细胞粘 附实验法,比较来自于健康人(26株)、糜烂型口腔扁平苔藓患者(62株)以及非糜烂型口腔扁平苔藓患者(24株)共 112株白色念珠菌对人颊细胞粘附力的大小。结果 糜烂型口腔扁平苔藓患者组的白色念珠菌分离株的平均粘附 数较健康对照组高(P

英文摘要

Objective To investigate the adhesion to buccal epithelial cells ofCandida albicansisolates from erosive oral li- chen planus(OLP) and nonerosive OLP, and its role in the development of OLP.Methods A total of 112 isolates, comprising healthy control (26),erosive OLP (62) and nonerosive OLP (24), were screened for the adhesion by using buccal epithelial cell (BEC) assay.Results The adhesion to buccal epithelial cells of the isolates from erosive OLP group was stronger than that of those from healthy control.Conclusion Candida albicans, some isolates with a special virulence attribute may contribute to the occurrence and progression of erosive OLP.

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