Objective The relationship between the mode of tumor invasion in the tumor-host borderline and the frequency of cervical lymph node metastasiswas investigated in squamous cell carcinoma of the oral cavity.Methods 200 caseswith histologi- cally proven squamous cell carcinoma of the oral cavitywere studied by histological methodwithHE stained. The mode of invasion in the tumor-host relationship was classified into five grades by Yamamoto′s criteria.Results With regard to the relationship be- tween the mode of invasion and metastasis, the more invasive the tumor tissue was, the more frequent the metastasis formed (P