Objective To study the coordination of facial soft tissue in Angle′s ClassⅠ、Ⅱ1、Ⅲmalocclusion, providing ref- erence for the clinical practice.Methods 60 lateral cephalometric radiographs of three classes of Angle′s malocclusion were in- cluded. 13 measurements were analyzed by SPSS 10.0.Results Protrusion of the upper and lower lips increased in Angle′sⅡ1 comparing with Angle′sⅠand protrusion of the upper lipwas larger than the lower lip, no difference was found in the facial conv- exity. Increase of upper lip inclination and underdevelopment of maxillary in Angle′sⅢcomparing with Angle′sⅠ.No significant differentwas found in the form of lower lip,soft tissue facial angle and Z angle. Comparing Angle′sⅡ1with Angle′sⅢ, every measurements were significantly different except upper lip inclination, nasolabial angle, representing the formation mechanism of malocclusion.Conclusion Some differences were found in form and position of lip in three classes of Angle′s malocclusion. However, the deformity was not obvious in Angle′sⅡ1and Angle′sⅢbecause of compensation mechanism. Nasolabial angle only reflected change of upper lip, but could not reflect characters of facial profile.