Objective To study the effect of Radix Scutellariae on the growth, metabolism ofPorphyromonas endodontalis (P.e), as a preparation for studying the mechanism of Radix Scutellariae in treating pulp and periapical diseases.Methods P.ewas chosen as the experimental bacteria. Radix Scutellariae was extracted by means of reflux with 80% ethanol. The value of MIC of Radix Scutellariae was measured by minute amount serial dilusion test, and the production of butyrate was measured by high liquid chromatograph(HPLC).Results Radix Scutellariae could inhibit the growth ofP.e, of which the MICwas 100 mg/ L. Following the increase in concentration of Radix Scutellariae, the amount of butyrate decreased to (3·527±0·009) mg/L, (3·048±0·005) mg/L, (2·490±0·011) mg/L, (2·209±0·016) mg/L, respectively(P
