Objective:The aim of this study was to investigate the effect of modified polyhydroxybutyrate membranes and polyhydroxybu- tyrate membranes (PHBm) on guided bone regeneration of fresh extract tooth sockets.Methods:The extract tooth socketswere es- tablished by extracted two premolars in each quadrant of a dog. The tooth sockets were covered with the modified PHBm, PHBm and without covering. The dogswere sacrificed in 1,2,3,6 months after surgery. Visual observation, radiography, SPECT, histo- logical inspection and tetracycline measurementwere carried out to evaluate the effects of these twomaterials on preserving alveolar ridge.Results:The results indicated that modified PHBm and PHBm improved the restoration of the socket and preserved the con- tour and height of the alveolar ridges.Conclusion:Modified PHBm and PHBm can be used in protecting extract tooth sockets and preserve alveolar ridges.
