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论文摘要

沈阳地区儿童变形链球菌群细菌母子传播的初步研究

A Primary Study of Mother-to-child Transmission of Mutans streptococciin Shenyang of China

作者:张晓芳,刘淑杰,许学斌

Author:Zhang Xiaofang, Liu Shujie,Xu Xuebin

收稿日期:2002-08-25          年卷(期)页码:2002,20(04):268-

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:变形链球菌,聚合酶链反应,母子传播,

Key words:Mutansstreptococci,arbitrarilyprimedpolymerasechainreaction,mother-to-child transmission,

基金项目:

中文摘要

目的:研究中国沈阳地区儿童变形链球菌群细菌(Mutans streptococci,MS)的母子传播情况。方法:选取16对母子的唾液,在选择培养基上培养后计数MS的菌落数量,用随机引物聚合酶链反应(arbitrarily primed polymerase chain reaction,AP-PCR)鉴定其基因型。结果:儿童口腔中5615%的MS基因型与母亲一致;而且母亲与儿童唾液MS 计数水平呈正相关关系。结论:沈阳地区儿童口腔MS主要来源于母亲。

英文摘要

Objective:The aim of this study was to investigate mother-to-child transmission ofMutans streptococciin Shenyang area of China.Methods:Saliva samples of 16 mothers and their children were collected and cultured on selective medium forMutans streptococci. Arbitrarily primed polymerase chain reactions (AP-PCR) with randomly chosen primers were performed to genotype these isolates.Results:The PCR results demonstrated thatMutans streptococciin 5412% of the mother/child pairswere the same in genotypes. Similargenotypes inmothers and childrenwere found significantly more frequently inmotherswho had more than one genotype. Significant correlation was found in colony forming units (CFU) between mothers and their children.Conclusion:This suggests thatMutans streptococcicould be transmitted frommothers to their children. Significant correlationwas found between the number of genotypes ofMutans streptococciin mothers and the transmission of this group of streptococci from mothers to their chil- dren.

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