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论文摘要

载银抗菌纯钛表面的制备及其抗菌性能的检测

Preparation and anti-bacterial tests of silver-modified titanium surface

作者:廖娟 费伟 郭俊 李鹏

Author:Liao Juan, Fei Wei, Guo Jun, Li Peng

收稿日期:          年卷(期)页码:2014,32(3):303-303-305

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:钛,纳米银,抗菌性能,水相硅烷化,

Key words:titanium,nano-silver,antibacterial activity,silanization method,

基金项目:

中文摘要

目的 对纯钛表面进行抗菌改性,以降低纯钛种植体周围炎的发生率,从而提高种植术的成功率。方法 采用水相硅烷化方法,将3-(氨基丙基)三乙氧基硅烷(APS)组装在湿化学法处理的钛表面上,并将纳米银被覆在该表面上,采用X射线光电子能谱(XPS)和X射线能谱(EDX)对该改性表面理化性能进行分析,观察其对金黄色葡萄球菌和大肠杆菌的抗菌性能。结果 扫描电镜观察可见,改性后的钛表面有不规则纳米银颗粒散在的附着在其表面上,XPS分析显示银的含量为6.8%。经过24 h需氧培养,纳米银改性钛片对金黄色葡萄球菌的抗菌率达到94.23%,对大肠杆菌的抗菌率达95.34%。结论 经过纳米银改性后的钛片具有抗菌性能。

英文摘要

Objective To deposit silver nanoparticles on a titanium surface to obtain antibacterial properties. To reduce the incidence of peri-implantitis, and improve the success rate of implantation.Methods A silver nanoparticle-modified titanium (Ti-nAg) surface was prepared using silanization method, and its surface was characterized by using X-ray photoelec-tron spectroscopy (XPS) and energy dispersive X-ray spectrometer (EDX). Two species of bacteria, namely, Staphylococcus aureus and Escherichia coli, were used to test the antibacterial effect of Ti-nAg surface.Results Scanning electron micro-scope (SEM) revealed that a small quantity of silver nanoparticles were deposited on the titanium surface. XPS analyses revealed that 6.8% of silver was present on the titanium surface. After 24 h of incubation, 94.23% of Staphylococcus aureus and 95.34% of Escherichia coli were killed on the Ti-nAg surface.Conclusion Results suggest that silver nanoparticle-modified titanium is a promising material with an antibacterial property that may be used as an implantable biomaterial.

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