Increasing numbers of microbiome studies have enabled the development of a greater understanding of how antagonistic and synergetic microbial interactions in?uence disease outcomes.Candida albicansis an opportunistic pathogen that is commonly found in human oral micro?ora. In a healthy oral environment,Candida albicansmay potentially but significantly influence the balance between the oral bacterial ecosystem and the host, leading tooral diseases. The aim of this study is to review the correlation betweenCandida albicansand oral pathogens and provide a deeper understanding of the nature of oral infectious diseases.