韦荣球菌与口腔疾病的研究进展

Veillonellaspecies, known as the early colonizer of oral biofilm, are prevalent in oral microbiota. SevenVeillonellaspecies have been isolated from oral cavity. Their distribution varies not only with different people but also with different sites in the oral cavity. OralVeillonellaare associated with oral diseases. They contribute to the adhesion ofStreptococcus mutansand consume the lactate generated by streptococci.Veillonellaspecies play an important role in the occurrence and development of periodontal diseases by providing adhesion sites forPorphyromonas gingivalisand boosting immune responses. The production of lipopolysaccharide and H₂S is related to other oral diseases, such as pulpitis, periapical periodontitis, and halitosis. Several studies have been conducted on the relationship betweenVeillonellaand oral diseases and the interaction betweenVeillonellaand other pathological microorganisms, but limited knowledge is available at the molecular level. This article reviews the research progress in the relationship betweenVeillonellaand oral infectious diseases, such as dental caries and periodontal diseases.