Objective To evaluate the methods of orthognathic treatment for mandibular asymmetry.Methods 110 cases of mandibular asymmetry had been treated in pastthirteen years. The type of deformity, the management of the cases, and the effects of orthognathic treatment were summarized in this paper. Orthodontic therapy was taken before and after operation to keep the treatment effect.Results Accordingtothe type of the asymmetry deformity, differentmethodswere used. Aftertreatment, all the patients obtained satisfactory facial appearances and oral function.Conclusion It should be diagnosed before surgerywhether the development of deformity is steady or not. If it is steady, the effects of orthognathic and orthodontic therapywill be satisfactory; if not, we should remove the affected condyles and simulataneously ameliorate facial appearance.