Objective The aim of this experiment is to know whether active orthopedic appliance is rationale to do presurgical treatment and seek some regularities. Methods Laser scanning confocal microscopy and triple fluorochrome labeling in bone were used to observe and study detailed changes occured in compressed suture systematically. Results Widened suture and broken fibres between the adjoining bones was observed at the 3ed week postoperatively. At the 3th week hyperplasia of organic tissue com- portents was also seen. At the 6 and 9th week there were no apparent differences among all groups no matter whether in control group or experimental groups. Conclusion Retarding injury of compressed suture and surrounding tissue hyperplasia exists. With growth and development wounded suture will gradually assimilate to control group structurally and functionally.