Objective:This study was to evaluate and compare the clinical effects of suction drainage and decompression on the treatment of odontogenic keratocysts (OKCs).Methods:Twenty cases of patients were divided into two groups, including 10 in the experi- ment group whowere treated with suction drainage (SG) and 10 in the control group whowere treated with decompression (DG). Clinical symptoms, radiographic findings and the thickness of newbone in these two groupswere evaluated and compared.Results: Significant differences of average decrease of cyst size between these two groups were observed two/six months after the therapy (P