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论文摘要

恶性成釉细胞瘤定量病理学研究

A Quantitatively Pathological Study on Malignant Ameloblastomas

作者:刘进忠,汪说之,陈新明

Author:Liu Jinzhong, Wang Shuozhi, Chen Xinming

收稿日期:2002-06-25          年卷(期)页码:2002,20(03):187-

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:恶性成釉细胞瘤,形态计量,DNA含量,核仁组成区,图像分析,

Key words:malignantameloblastoma,morphometry,DNAcontent,AgNORs,imageanalysis,

基金项目:

中文摘要

目的:探讨恶性成釉细胞瘤细胞核形态参数、DNA含量及AgNOR形态分型和计数在诊断中的意义。方法: 选取17例恶性成釉细胞瘤患者的切除标本行HE、AgNOR及DNA染色,应用图像分析仪对细胞核形态几何参数、 DNA含量及倍体、AgNOR进行定量分析。结果:在细胞核的几何参数中,恶性成釉细胞瘤细胞的面积、周长、等圆直径、短径、平均直径、圆度、轴比与良性成釉细胞瘤均有显著性差异(P

英文摘要

Objective:The purpose of this study was to investigate the role of nuclear morphometric parameters, DNA content and Ag- NOR count in the differentiating malignant and benign ameloblastomas.Methods:Totally 17 cases of malignant ameloblastomas were examined by using HE, AgNOR and DNA stain methods. Morphometric parameters of cell nuclei, DNA content and AgNOR countwere quantitatively studied by using an image analysis system.Results:Seven parameters (area, perimeter, equal diameter, minor diameter, mean diameter, round index, axis ratio) out of ten shape factors were significantly different between malignant and benign ameloblastoma (P

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