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论文摘要

血清β-羟丁酸在糖尿病酮症/酮症酸中毒中的诊断价值

The Diagnostic Value of Serum Beta-hydroxybutyrate in Diabetic Ketosis or Diabetic Ketoacidosis

作者:杨惠岚, 袁高品, 邓浩等

Author:YANG Hui-lan, YUAN Gao-pin, DENG Hao. et al

收稿日期:          年卷(期)页码:2014,45(2):270-273

期刊名称:四川大学学报(医学版)

Journal Name:JOURNAL OF SICHUAN UNIVERSITY (MEDICAL SCIENCE EDITION)

关键字:血清β羟丁酸 尿酮体 糖尿病酮症 糖尿病酮症酸中毒 Logistic回归 ROC曲线

Key words:Serum beta-hydroxybutyrate Urine ketone Diabetic ketosis Diabetic ketoacidosis

基金项目:

中文摘要

目的 探讨血清β-羟丁酸在糖尿病酮症/酮症酸中毒(DK/DKA)中的意义和诊断价值。方法 回顾2011年5月至2013年5月四川大学华西医院内分泌科1 209例糖尿病无酮症患者(DM组),262例患者(DK/DKA组)和480例同时期行体检的健康对照者(正常对照组)的临床资料,采用logistic回归及ROC曲线判断β-羟丁酸的诊断价值。结果 DK/DKA组患者血清β-羟丁酸水平高于DM组和正常对照组(P P

英文摘要

【Abstract】 Objective To determine the diagnostic value of serum beta-hydroxybutyrate (βOHB) in diabetic ketosis or diabetic ketoacidosis. Methods We conducted a retrospective review of clinical data, in West China Hospital from May 2011 to May 2013, of 1 209 patients with non-ketosis diabetics (DM group), 262 patients with diabetic ketosis or diabetic ketoacidosis (DK/DKA group), and 480 healthy people undergoing routine medical examinations (normal control group). Logistic regression analyses and ROC curves were performed in determining the diagnostic value of βOHB for DK/DKA. Results The level of serum βOHB was much higher in the DK/DKA patients than that of the participants in the DM group and normal control group (PP

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