Objective To determine the expression of microRNA-152 induced by progesterone and its effect on the proliferation of endometrial epithelial cells (EECs). Methods Cultured EECs, Ishikawa were divided into four groups: control group (C group), 10-8mol/L estrogen treated group (E group), 10-6mol/L progesterone group (P group) and estrogen plus progesterone treated group (E&P group). The expression of mature microRNA-152 （microRNA-152-3p）of was detected by qRT-PCR. The estrogen treated cells were transfected with mimic-microRNA-152-3p. The estrogen and progesterone treated cells were transfected with inhibitor-microRNA-152-3p. Cell proliferations were detected by CCK-8 assay. The target gene of microRNA-152-3p proteins was predicted using microRNA target databases and validated by Western blot. Results qRT-PCR showed no difference between C and E groups ( P>0.05) in the expression of microRNA-152-3p. P group had higher expressions of microRNA-152-3p than C group ( P
