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论文摘要

双J管管壁结石形成影响因素的横断面研究

The Cross-sectional Study on the InfluenceFactors for Encrustation of Double J Stent in Patients with Urolithiasis

作者:曹祥明, 刘嘉铭, 廖邦华等

Author:CAO Xiang-ming, LIU Jia-ming, LIAO Bang-hua. et al

收稿日期:          年卷(期)页码:2015,46(3):431-435

期刊名称:四川大学学报(医学版)

Journal Name:JOURNAL OF SICHUAN UNIVERSITY (MEDICAL SCIENCE EDITION)

关键字:双J管 管壁结石 影响因素

Key words:Double J stent Encrustation Influencing factors

基金项目:

中文摘要

目的 了解双J管管壁结石形成的基本情况,探讨分析双J管管壁结石形成的影响因素。 方法 纳入2014年2~7月在我科因上尿路结石接受输尿管软镜联合钬激光碎石术的患者共84例,收集相关临床资料,使用电脑体式显微镜观测双J管管壁结石形成情况,对临床资料与管壁结石形成之间的关系采用t检验、χ2检验、Fisher确切概率法、logistic回归进行统计学分析。 结果 双J管平均留置时间(17.0±6.0) d,67例(79.8%)双J管形成管壁石膜。石膜形成组较未形成石膜组更年轻〔(44.9±11.5)岁 vs. (54.4±12.6)岁,P=0.004〕;尿蛋白阳性患者的管壁石膜形成率更高〔62/73(84.9%) vs. 5/11(45.5%),P=0.002〕;尿路感染阳性者较阴性者石膜形成率高〔26/28(92.9%) vs. 41/56(73.2%), P=0.035〕;血尿阳性者较阴性者石膜形成率高〔67/80(83.8%) vs. 0/4,P=0.001〕。不同性别、双J管留置时间、血清钙、无机磷、尿酸、尿pH、结石类型之间石膜形成率差异无统计学意义(P>0.05)。取5例双J管管壁结石进行结石成分分析,发现与原发结石成分完全一致。Logistic回归发现石膜形成与低龄和尿蛋白相关(PP>0.05)。结论 影响管壁石垢形成的因素众多,尿蛋白阳性和低龄是双J管表面结石形成的重要危险因素。

英文摘要

Objective To study the influence factors for encrustation of double J stent in patients with urolithiasis. Methods In this study, there were 84 urolithiasis patients with double J stent included from February to July 2014 in our hospital. The encrustation on double J stent was evaluated by a PC stereo microscope. The interrelated clinical data were obtained, then the factors which may affect the encrustation were studied by logistic regression analysis. Results The mean indwelling time was (17.0±6.0) d, and a thin encrustation formed on the stents for most cases 〔67/84(79.8%)〕. Compared with the cases who did not form a thin encrustation, those having a thin encrustation formation on the stent were younger 〔(44.9±11.5) vs. (54.4±12.6),P=0.004〕. The patients with proteinuria got a higher rate of encrustation 〔62/73(84.9%) vs. 5/11 (45.5%),P=0.002〕.The patients with urinary tract infection had a higher rate of encrustation 〔26/28(92.9%) vs. 41/56(73.2%), P=0.035〕. The patients with hematuriaalso got a higher rate of encrustation 〔67/80(83.8%) vs. 0/4,P=0.001〕。Different sex, retention time,serum calcium,inorganic phosphorus,uric acid,urine pH,lithiasis component had no effects on encrustation (P>0.05). Logistic regression analysis showed that age and proteinuria was retained as independent correlated factors with encrustation (PP>0.05). Conclusion For encrustation of double J stentin patients with urolithiasis, younger age, increased urinary protein, hematuria and infections are important risk factors.

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