Objective To investigate the carrying rates and genotype distribution of thalassemia gene in Han people and Tibetans in Sichuan district. Methods A total of 1 147 Han adults and 613 adult Tibetans were included in this study. Hematological parameters were measured with Sysmex XE-2100 automatic blood cell analyzer. Alpha thalassemia and beta thalassemia gene analyses were further performed on samples with a mean corpuscular volume (MCV) --SEA/αα as the most common genotype; 1.39% (16/1 147) carried beta thalassemia gene, with CD17 and IVS-Ⅱ-654 as the most common genotype. There were 2 cases with both alpha and beta thalassemia. Low MCH (
