Cellulose, as the most abundant renewable resource on earth, is an ideal raw material for producing various functional materials, because of its biodegradability, biocompatibility, non-toxicity, low-cost, environmental friendliness and safety risks. Based on the utilization of cellulose resources, the review introduced the recent advances in cellulose-based functional materials, focusing on the function and application of four major morphological cellulose materials:including research progress in the field of adsorption separation and protein immobilization based on unique spherical spatial configuration and network structure of cellulose microspheres. Research progress in the fields of medical, intelligent, electrode and separation materials based on the superior biocompatibility of cellulose hydrogel and the three-dimensional porous structure of cellulose aerogel. Research progress in the field of high performance plastics, optoelectronics and smart materials based on high transparency and toughness of cellulose film. Research progress in the field of textiles and electronic materials based on the high toughness, woven, and low density of cellulose fibers. Finally, the perspectives for the future development of cellulose-based materials were put forward, and the key scientific problems that need to be solved in the application-oriented research process of the above four morphological cellulose-based functional materials were discussed. We hope that this work could provide valuable reference and guidance for future design and application on functional cellulose-based materials.