In various process industries such as chemical production and petrochemical industry, the interphase heat (mass) transfer in many systems is involved. The exploration of enhanced transfer process has become the focus and hot spot of research. As a new technology to effectively enhance the heat and mass transfer between phases and promote micro-mixing, impinging stream has shown good application prospects in the fields of absorption, crystallization and ultra-fine powder preparation and so on. Based on the author’s years of experience in the field of impinging stream and research results, the research progress of impinging stream technology and the development of new reactors were reviewed. Using LDA, PDA, PLIF and other advanced visual testing techniques, the rich information such as pressure fluctuation, instantaneous and time-average velocity and concentration signal in the impinging stream field under different structural arrangements were extracted, and the macroscopic pressure, velocity and concentration distribution of the flow field were obtained. At the same time, the role of each physical parameter in the fluid mechanics equations was accurately grasped. The chaotic analysis, fractal analysis, wavelet transform and Hilbert-Huang transform were used to identify the chaotic and random components of the signal, calculate the quantitative description of nonlinear characteristic parameters, such as correlation dimension, Kolmogorov entropy, Lyapunov exponent and Hurst exponent and clarify the macroscopic motion characteristics, heat transfer, mass transfer and reaction effects of flow field. In addition, the indicators such as separation degreeIOSand plane mixing uniformityUwere introduced to quantitatively characterize the mixing and oscillation characteristics of impinging stream mix-reactor under different structural characteristic parameters (nozzle diameterd, nozzle spacingL, etc.), and determine the best working conditions for mixing.Through the above research, the theory of complex turbulence system was constantly improved. Combined with FLUENT numerical simulation software, experiments and theories confirm each other, providing guiding parameters for the optimization of the structure of the impinging stream reactor and the development of new equipment. Based on this, the author has independently developed multiple sets of coaxial impinging mix-reactor and horizontal three-way impinging stream mix-reactor with intellectual property and establishing a two-component layer impinging stream reactor as the core to establish an industrial scale demonstration device for preparation of ultrafine powder, which provides a new idea for the development and application of impinging stream technology in industry. Finally, it was pointed out that the complex impinging stream mix-reactor that explores synergy with other advanced technologies (ultra-high pressure, supercritical, etc.) has become a major direction for future research and development.